Hapsite Gas Chromatography - Mass Spectrometry with Solid Phase Microextraction

Abstract

Rapid air sampling can be accomplished with solid phase microextraction (SPME) to avoid the difficulties of pumps and wet chemistry. Gas chromatography with mass spectrometry (GC/MS) is the gold standard for identifying volatile and semi volatile chemicals. Combining SPME with a portable HAPSITE GC/MS may allow rapid chemical identification outside of a laboratory. Six chemicals at six concentrations were tested using four sample introduction methods. The four methods included the HAPSITE loop, the HAPSITE with tri-bed concentrator, the HAPSITE with SPME and a field portable GC/MS with SPME. The SPME fiber used was Polydimethylsiloxane (PDMS). The HAPSITE with tri-bed concentrator achieved the lowest detection limits. The HAPSITE and the field portable GC/MS instrument coupled with SPME had similar variability. The relative standard deviation for these instruments was under 25% for most chemicals with concentrations between 1-10 ppm.

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Document Details

Document Type
Technical Report
Publication Date
Jul 18, 2005
Accession Number
ADA435802

Entities

People

  • Gary L. Hook
  • Waikwong Kan

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alkenes
  • Boiling Point
  • Chemical Synthesis
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemistry
  • Chromatographs
  • Data Analysis
  • Desorption
  • Detection
  • Detectors
  • Environment
  • Environmental Protection
  • Mass Spectrometry
  • Organic Chemistry
  • Spectrometry
  • Volatile Organic Compounds

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry