Real Time Biodetection of Individual Pathogenic Microorganisms With a Rugged, Sub-Briefcase-Sized System

Abstract

The objective of this research is to test the feasibility of an innovative approach to rare cell detection: using a CCD to image an entrained flow through a rectangular glass tube. This approach is especially useful for the detection of rare cells where a high volumetric flow rate is desired. We present the results of our work with Nile red labeled 1-micron polystyrene beads as labeled cell simulants. This technique has key advantages over current alternatives, including: (1) high volumetric flow rate, 2)capability of detecting single microorganisms (3) automatic operation, and (4) easy implementation in a rugged, portable system.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2002
Accession Number
ADA436034

Entities

People

  • Amanda S. Votaw
  • Dehua Zhao
  • Jerome E. Swanson
  • Julie L. Kellogg
  • Michael L. Lund
  • Paul E. Johnson
  • Richard W. Shorthill
  • William Asprey

Organizations

  • University of Wyoming

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Abstracts
  • Charge Coupled Devices
  • Detection
  • Detectors
  • Dielectric Polymers
  • Electronics
  • Flow Rate
  • Geometry
  • Images
  • Laser Beams
  • Lasers
  • Measurement
  • Microorganisms
  • Microscopes
  • Polystyrenes
  • Scattering
  • Two Dimensional

Readers

  • Aerosol Science/Aerosol Physics
  • Sensor Fusion and Tracking Systems.
  • Systems Analysis and Design