Development of Medical Countermeasures to Sulfur Mustard Vesication

Abstract

Sulfur mustard (HD) is an alkylating agent with cytotoxic, mutagenic and vesicating properties. It use on the battlefield results in debilitating injuries to skin, eyes and the respiratory system (1, 2). To elucidate the toxic sequelae that follow cutaneous exposure to HD, the United States Army Medical Research Institute of Chemical Defense (USAMRICD) has undertaken a broad-based research program encompassing both intramural and extramural research. This report summarizes our current understanding of the toxicology of human exposure to HD based on in vitro and in vivo experimental models.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2002
Accession Number
ADA436060

Entities

People

  • Michael C. Babin
  • Robert P. Casillas
  • Robyn C. Kiser
  • William J. Smith

Organizations

  • United States Army Medical Research Institute of Chemical Defense

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Biomedical Research
  • Cell Physiological Processes
  • Cells
  • Countermeasures
  • Databases
  • Enzyme Inhibitors
  • Inhibition
  • Inhibitors
  • Intervention
  • Medical Countermeasures
  • Modulators
  • Pathology
  • Rodents
  • Test And Evaluation
  • Vesicants

Readers

  • Geochemistry
  • Oncology (Cancer Research).
  • Technical Research and Report Writing.