Determination of Thiodiglycol in Groundwater Using Solid Phase Extraction Followed by Gas Chromatography with Mass Spectrometric Detection in the Selected Ion Mode

Abstract

A highly-sensitive analytical procedure is described for determining thiodiglycol in groundwater. Samples are initially fortified with 3,3 -thiodipropanol (surrogate), then both species are extracted using sequential solid phase extraction with C18 and Ambersorb 572 columns in tandem. The C18 column, which removes extraneous groundwater components, is discarded; the Ambersorb 572 column is dried thoroughly before eluting polar components with a small volume of dichloromethane. The extract is taken to dryness using dry flowing nitrogen, and the resulting residue is derivatized using MTBSTFA and pyridine. The derivatized products are diluted to a final volume with toluene, chromatographed using a fused-silica capillary column, and detected with a quadrupole mass spectrometric detector in its selectedion mode. Two independent statistically unbiased procedures were used to evaluate the detection limits for thiodiglycol; the values ranged between 4 and 16 mg L-1 groundwater.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2002
Accession Number
ADA436090

Entities

People

  • Bruce A. Tomkins
  • Gary A. Sega

Organizations

  • Oak Ridge National Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Synthesis
  • Chemistry
  • Chromatographs
  • Chromatography
  • Detection
  • Detectors
  • Environmental Protection
  • Extraction
  • Gas Chromatography
  • Liquid Chromatography
  • Mass Spectrometers
  • Mass Spectrometry
  • Organic Chemistry
  • Rocky Mountains
  • Solid Phases
  • Spectrometers
  • Spectrometry

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  • Analytical Chemistry