Integration of Analytic and Synthetic Biosystem Models and Data

Abstract

This effort, funded under DARPA's Biocomputing (BioComp) program, was directed at providing data services for the BioSpice infrastructure. BioSpice is an environment akin to the Electrical Engineering SPICE modeling and simulation package, in which an open environment and standards-based modularity enable an enormous range of tools for the development and understanding of electronic circuits to be applied without restrictions resulting from proprietary or closed interfaces. BBN also teamed with the University of Pennsylvania to develop an intuitive tool called BioSketchpad, for creating and parameterizing models and connecting the resulting models to a simulator. A modeling language (Systems Biology Markup Language (SBML), was also developed for representing interesting molecular biology models and to support model interchange between different tools. The SBML effort required collaboration with a separate systems biology development effort (which had created the first version of SBML) that was an outgrowth of other research efforts.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2005
Accession Number
ADA436193

Entities

People

  • Jonathan Delatizky
  • Jonathan Webb

Organizations

  • BBN Technologies

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  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Biology
  • Chemistry
  • Computational Biology
  • Computer Programming
  • Computers
  • Configuration Management
  • Databases
  • Electrical Engineering
  • Engineering
  • Engineers
  • Fungi
  • Genetics
  • Language
  • Molecular Biology
  • Simulators
  • Systems Biology
  • Systems Engineering

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  • Database Systems and Applications
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Research Science/Academic Research

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  • Microelectronics