Development and Evaluation of a Percutaneous Technique for Repairing Proximal Femora with Metastatic Lesion
Abstract
Metastatic lesions in the proximal femur are a common and serious manifestation of breast cancer. These lesions can be painful and can lead to pathological fracture. Prophylactic surgical fixation is advised in those patients thought to be at high risk of fracture and typically involves placement of a prosthetic implant or a compression hip screw to provide strength. In this study, we are investigating whether proximal femora with metastatic lesions can be repaired by simply filling the defect with bone cement (polymethylmethacrylate), an innovative procedure that could be performed percutaneously and could eliminate the need for implanting hardware in many cases. If the metastatic defect could be safely repaired using this new technique, the patient would benefit from a shorter and less invasive surgical procedure, less pain and discomfort, greatly reduced recovery time, and a shorter hospital stay all at much lower cost. Using finite element (FE) analysis, this study will also develop clinical guidelines both for assessing the need for prophylactic fixation and for using the proposed percutaneous surgical procedure. This extensive evaluation will enable rapid and safe clinical implementation of the new repair technique and surgical guidelines via a clinical trial immediately following this study.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2005
- Accession Number
- ADA437176
Entities
People
- Joyce H. Keyak
Organizations
- University of California, Irvine