Efficacy of Calcium and Vitamin D Supplementation for the Prevention of Stress Fractures in Female Naval Recruits
Abstract
The goal of this project is to determine if calcium and vitamin D intervention can reduce the incidence of stress fracture by at least 50% in female Naval recruits during basic training. We will recruit 5200 recruits who will be randomly assigned to an intervention group given calcium 2000 mg and vitamin D 800 I.U. per day or a control placebo group. The recruit intervention and stress fracture monitoring will continue through 8 weeks of basic training. Positive findings from this study would provide support for the Navy to adopt an easy, low cost method of further decreasing incidence of stress fractures. In May 2004, the DOD approved our protocol amendment to perform peripheral quantitative computed tomography (pQCT) measurements on a subset of recruits. The purpose of the substudy is to examine potential mechanisms for increasing bone adaptation to intense mechanical loading. We are performing the pQCT measurements. To date we have enrolled 4454 female recruits into the study, and 3518 have completed. We are retaining about 79% of enrolled participants. We have no findings to date.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2004
- Accession Number
- ADA437677
Entities
People
- Joan M. Lappe
Organizations
- Creighton University