Are Individual Differences in Fatigue Vulnerability Related to Baseline Differences in Cortical Activation

Abstract

Recent evidence suggests that underlying patterns of cortical activation may partially account for individual differences in susceptibility to the effects of sleep deprivation. Here, functional magnetic resonance imaging (fMRI) was used to examine the activation of military pilots whose sleep-deprivation vulnerability previously was quantified. A Sternberg Working Memory Task (SWMT; S. Sternberg, 1966) was completed alternately with a control task during a 13-min blood oxygen level-dependent fMRI scan. Examination of the activated voxels in response to SWMT indicated that, as a group, the pilots were more similar to fatigue-resistant nonpilots than to fatigue-vulnerable pilots. Within the pilots, cortical activation was significantly related to fatigue vulnerability on simulator-flight performance. These preliminary data suggest that baseline tMRI scan activation during a working memory task may correlate with fatigue susceptibility.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2005
Accession Number
ADA437682

Entities

People

  • Alexander Mishory
  • David L. Brown
  • Gordon Peters
  • J. L. Caldwell
  • Jennifer K. Smith
  • John A. Caldwell
  • Mark S. George
  • Qiwen Mu

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical
  • Engineered Resilient Systems
  • Human Systems
  • Space

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Brain
  • Data Analysis
  • Flight Simulators
  • Human Factors Engineering
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Medical Personnel
  • Military Pilots
  • Neuroimaging
  • Psychology
  • Simulations
  • Simulators
  • Sleep Deprivation
  • Test Facilities
  • Vulnerability

Fields of Study

  • Psychology

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Medical Imaging.
  • Neuroscience