Enhanced Ultrasound Visualization of Brachytherapy Seeds by a Novel Magnetically Induced Motion Imaging Method
Abstract
The authors report on their progress in developing Magnetically Induced Motion Imaging (MIMI) for unambiguous identification and localization of brachytherapy seeds in ultrasound images. Ultrasound guided brachytherapy is a common treatment for prostate cancer. Accurate determination of seed location is critical for the delivery of the correct radiation dose distribution to the prostate. They report initial results from their finite-element model, which provides an estimate of the torque required for a given seed displacement and an optimum seed vibration frequency of 310Hz. They have determined that the tissue vibration isosurfaces shrink with increasing frequency and have developed tools to measure them. Major results are the development of a finite-element model of a brachytherapy seed embedded in tissue, and the development of Matlab code to simulate the ultrasound echoes arising from tissue motion extracted from the finite-element model. Automatic seed segmentation and real-time dose planning are enabled by this technique. Furthermore, the technique enables ultrasound to replace CT for post-implant evaluation by providing a mechanism by which implanted seeds may be reliably identified by ultrasound. This report documents activities related to this grant for the period 1 April to 30 June 2004. Work on this grant was halted and all expenditures stopped at the end of June 2004 as a result of the transfer of the PI, Stephen McAleavey, from Duke University to the University of Rochester. No grant money has been spent since June, nevertheless, progress has been made in the short time the project was active.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2005
- Accession Number
- ADA438155
Entities
People
- Stephen McAleavey
Organizations
- Duke University