Magnetic Resonance and Spectroscopy of the Human Brain in Gulf War Illness

Abstract

The goal of this project is to test the hypotheses that: 1) Subjects with GWI have reduced NAA in the basal ganglia and pons, which are not accounted for by confounds such as PTSD, depression, and alcohol abuse. 2) Reduced NAA in basal ganglia and pons correlates with CNS signs and symptoms of GWI Thus far, we have mailed out a total of 2319 recruitment letters describing our study. Dr. Weiner has appeared on several radio and TV programs in response to our press release. Over 488 subjects have contacted us expressing interest in this study. Study procedures include a medical evaluation, clinical assessments, neurocognitive testing, startle testing, MRI/MRSI, and the "Haley Questionnaire." To date, we have studied a total of 176 subjects, 150 of whom have data for analysis. Of this total, 39 met criteria for GWI, 54 are controls, and 57 have an intermediate classification. We currently have 10 subjects scheduled for the remainder of the month, Although some preliminary data analysis has been performed, the current sample size is much too small for formal data analysis.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2004
Accession Number
ADA438498

Entities

People

  • Michael Weiner

Organizations

  • Northern California Institute for Research and Education

Tags

DTIC Thesaurus Topics

  • Alcohol Consumption
  • Biomedical Research
  • Brain
  • California
  • Central Nervous System
  • Classification
  • Data Analysis
  • Department Of Defense
  • Depression
  • Education
  • Hydrolysis
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Nervous System
  • Persian Gulf Syndrome
  • Resonance
  • Signs And Symptoms

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Neuroscience