Developmental Toxicity of Drinking Water Disinfection By-Products to Embryos of the African Clawed Frog (Xenopus laevis)

Abstract

Water chlorination is a standard treatment for ensuring the safety of public drinking water. One drawback to this beneficial practice is the generation of drinking water disinfection by-products (DWDB), some of which have been implicated as causing adverse human health outcomes. In this article, we report the results of 96 hours of developmental toxicity tests with embryos of the South African clawed frog 'Xenopus laevis' used to evaluate four individual DWDB: bromodichloromethane (BDCM), sodium chlorate, chloroform, and dibromoacetic acid (DBAA). These chemicals were selected for testing based on their potential for human harm and as representatives of byproducts of different disinfection processes.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 10, 2005
Accession Number
ADA441154

Entities

People

  • A. B. Rosencrance
  • C. M. Brown
  • D. M. Kumsher
  • H. S. Gardner
  • L. M. Brennan
  • M. W. Toussaint
  • W. E. Dennis
  • W. H. Van Der Schalie

Tags

DTIC Thesaurus Topics

  • Army Corps Of Engineers
  • Chlorination
  • Chlorine Compounds
  • Chloroform
  • Data Science
  • Demographic Cohorts
  • Detection
  • Digestive System Processes
  • Disinfection
  • Drinking Water
  • Environmental Health
  • Health
  • Pregnancy Complications
  • Standards
  • Test Methods
  • Toxicity
  • Water Supplies

Fields of Study

  • Environmental science

Readers

  • Aquatic Ecology
  • Environmental Engineering
  • Toxicology/Environmental Toxicology