Methods of Analysis by the U.S. Geological Survey Organic Geochemistry Research Group - Determination of Glyphosate, Aminomethylphosphonic Acid, and Glufosinate in Water Using Online Solid-Phase Extraction and High-Performance Liquid Chromatography/Mass Spectrometry

Abstract

An analytical method for the determination of glyphosate, its principal degradation compound, aminomethylphosphonic acid (AMPA), and glufosinate in water with varying matrices has been developed. Four different sample matrices forti ed at 0.2 and 2.0 g/L (micrograms per liter) were analyzed using precolumn derivatization with 9- uorenylmethylchloroformate (FMOC). After derivatization, cleanup and concentration were accomplished using automated online solidphase extraction followed by elution with the mobile phase allowing for direct injection into a liquid chromatograph/mass spectrometer (LC/MS). Analytical conditions for MS detection were optimized, and quantitation was carried out using the following representative ions: 390 and 168 for glyphosate; 332, 110, and 136 for AMPA; and 402, 180, and 206 for glufosinate.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2002
Accession Number
ADA441991

Entities

People

  • A. P. Strahan
  • E. A. Lee
  • E. Michael Thurman

Organizations

  • United States Department of the Interior

Tags

DTIC Thesaurus Topics

  • Chemical Analysis
  • Chemistry
  • Chromatographs
  • Chromatography
  • Detection
  • Extraction
  • Geochemistry
  • Geological Surveys
  • Liquid Chromatography
  • Mass Spectrometers
  • Mass Spectrometry
  • Materials
  • Solid Phases
  • Spectrometers
  • Spectrometry
  • Surveys
  • Water Quality

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry