Obesity and Breast Cancer

Abstract

This is a Pilot Award to design a Breast Cancer of Excellence Pilot on the single, unifying question, "What are the roles of obesity in affecting breast cancer risk and mortality?" This question is the cornerstone of our proposed Center and is relevant to the prevention, detection, diagnosis and treatment of breast cancer, More specifically, we will study the interactions among timing of obesity, hormones, and breast cancer risk in minority and Caucasian populations and in appropriate animal models. Consistent with the goals of this award mechanism, we will use this pilot to build teams of consumers and leading investigators, in multiple research areas across several institutions in the U.S. and abroad, who will design innovative and imaginative approaches to addressing our overarching goal. We have commitments from consumers, computer scientists, engineers, biostatisticians, epidemiologists, endocrinologists, radiologists, medical oncologists, pathologists, behavioral scientists, and nutritionists. We will apply state-of-the-art technologies including high throughput genotyping, molecular profiling and tumor tissue arrays, digital mammography, magnetic resonance imaging, nanotechnology, bioinformatics, and biostatistics. This represents a unique mix of expertise and institutions, and includes both leading scientists and young investigators poised to address this critical problem in breast cancer research, treatment, and prevention.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2005
Accession Number
ADA442187

Entities

People

  • Robert R. Clarke

Organizations

  • Georgetown University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • African Americans
  • Biomedical Research
  • Body Weight
  • Breast Cancer
  • Computer Science
  • Consumers
  • Department Of Defense
  • Health Care
  • Health Services
  • Human Population
  • Intervention
  • Mammary Glands
  • Medical Personnel
  • Neoplasms
  • Overweight
  • Scientists

Readers

  • Defense Technology Research and Development.
  • Oncology and Biomarker-Based Cancer Detection.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology