Genetic and Hormonal Risk Factors for Prostate Cancer in African American Men
Abstract
African American men are at greater risk for developing and dying from prostate cancer compared to white men. This disparity is likely due to a number of factors including environmental and genetic factors. The Flint Men's Health Study (FMHS) was established in 1995 as a population-based case-control study of African American men aged 4C-%9 residing in Genesee County, Michigan. The initial sample consisted of V3O men who completed an in-home interview consisting of potential risk factors for prostate cancer; medical history; and demographic data. 431 men provided a blood sample and 3%9 men who were determined to be free of cancer completed a comprehensive urologic exam. Additionally, 119 cases of prostate cancer have been identified from the same population. Studies have suggested a role for hormones and genetics in cancer incidence. However, studies have been completed in white populations and results have been conflicting. The objective of this study is to more clearly delineate the potential role(s) of selected hormones %nd growth factors in prostate cancer development.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2005
- Accession Number
- ADA442683
Entities
People
- Aruna V. Sarma
Organizations
- University of Michigan