Intermittent Ultrasound Imaging of Prostate Cancer
Abstract
This study proposed to evaluate contrast-enhanced ultrasound imaging with a microbubble contrast agent in 300 subjects in order to improve the detection of prostate cancer. Between October 2001 and January 2004 a total of 301 subjects were enrolled. Laboratory blood tests (PSA) and ultrasound evaluations were completed on all 301 subjects (including the primary ultrasound interpretation worksheet). Independent blinded readers have reviewed imaging on all subjects. Pathological review for the presence and grade of cancer has been completed for all subjects. CD31 staining for micro-vessel density has been performed on the first 40 subjects. All available data has been entered into a computer database using an Excel spreadsheet. Analysis of the prostate cancer detection data from all 301 subjects was incorporated into a manuscript that has been accepted for publication in the journal "Cancer". The final analysis of microvessel density has been accepted for presentation at the annual meeting of the Radiological Society of North America (Dec 2005). Copies of the manuscript and the abstract are appended to this report.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2005
- Accession Number
- ADA443045
Entities
People
- Ethan J. Halpern
Organizations
- Thomas Jefferson University