Effects of Sample Impurities on the Analysis of MS2 Bacteriophage by Small-Angle Neutron Scattering

Abstract

Small angle neutron scattering (SANS) has been used to extend the structural characterization of the MS2 phage by examining its physical characteristics in solution. The impact of small molecular weight impurities of the resolution of structural data obtained by SANS of the bacteriophage MS2 distorts the resolution and sharpness of contrast variation peaks. However, the position of the visible peaks is unchanged contaminated samples when compared to pure MS2 samples.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2005
Accession Number
ADA443366

Entities

People

  • Catherine O'connell
  • Charles H. Wick
  • Deborah A. Kuzmanovic
  • Ilya Elashvili
  • Susan Krueger

Organizations

  • Edgewood Chemical Biological Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bacteriophages
  • Chemical Synthesis
  • Chemistry
  • Detectors
  • Iridoviridae
  • Leviviridae
  • Microbiology
  • Microbiomes
  • Molecular Biology
  • Molecular Weight
  • Neutron Scattering
  • Proteins
  • Ribonucleic Acids
  • Rna Phages
  • Viral Structures
  • Virology
  • Viruses

Fields of Study

  • Chemistry

Readers

  • Materials Science and Engineering.
  • Mathematics or Statistics
  • Powder metallurgy of Titanium alloys.