Digital Mammography: Development of an Advanced Computer-Aided Diagnosis System for Breast Cancer Detection

Abstract

The goal of the project is to develop computer-aided diagnosis (CAD) methods and systems for mammography using advanced computer vision techniques and image information fusion from multiple mammograms to improve lesion detection and characterization. When tally developed, the CAD system can assist radiologists in mammographic interpretation. During this project year, we have performed the following tasks: (1) collected databases of digital mammograms (DMs) and digitized film mammograms (DFMs) for development of the CAD systems, (2) developed computer vision techniques and a prototype CAD system for detection of microcalcifications on DMs, (3) developed computer vision techniques and a prototype CAD system for detection of masses on DFMs and DMs, (4) explored the feasibility of improving mass detection by CAD on digital breast tomosynthesis mammograms, (5) developed automated pectoral muscle detection method for preprocessing of MLO view mammograms for multiple image analysis, (6) developed a prototype CAD method for classification of malignant and benign masses by fusion of information from mammograms and ultrasound images and investigated the effects of the multi-modality CAD system on radiologists performance. In summary, we have investigated a number of areas in CAD of mammographic lesions and evaluated the new techniques for both DMs and DFMs. We have made progress in the six tasks proposed in the project. We have found that our new computer-vision techniques and two-view information fusion approach can improve the performance of the CAD systems. We will continue the development of the CAD systems for DMs and DFMs in the coming years.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 01, 2005
Accession Number
ADA443621

Entities

People

  • Heang-Ping Chan

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Advanced Electronics
  • C4I
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Computer Vision
  • Computers
  • Data Science
  • Databases
  • Detectors
  • Diagnostic Imaging
  • Digital Images
  • Health Services
  • Image Processing
  • Information Processing
  • Information Science
  • Institutional Review Board
  • Medical Personnel
  • North America
  • Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Sensor Fusion and Tracking Systems.

Technology Areas

  • AI & ML