Prevention and Treatment of ER-Negative Breast Cancer

Abstract

We have made very significant progress since the last report (two years) towards achieving the objectives of this Center as set out in the aims of the original proposal. In response to the need to develop targeted approaches for the prevention and treatment of ER- breast cancer we have organized the COE into six integrated Projects (P 1-6) that are supported by two Cores (C1-2). These projects span epidemiology, pathology, functional genomics, cancer cell biology, preclinical drug development, and chemoprevention. The overall aim of the COE is to understand the causes and critical pathways underlying the development of ER- breast cancer in order to develop novel strategies for prevention and treatment.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2005
Accession Number
ADA443711

Entities

People

  • Myles A. Brown

Organizations

  • Dana–Farber Cancer Institute

Tags

DTIC Thesaurus Topics

  • Biological Markers
  • Biomedical Research
  • Blood
  • Breast Cancer
  • Carcinoma
  • Cell Physiological Processes
  • Cells
  • Cellular Structures
  • Chromosomes
  • Diseases And Disorders
  • Epithelial Cells
  • Genetics
  • Growth Factors
  • Health Services
  • Neoplasms
  • Sex Hormones

Fields of Study

  • Biology

Readers

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  • Molecular and genetic basis of cancer.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology