Magnetic Resonance and Spectroscopy of the Human Brain in Gulf War Illness

Abstract

The goal of this project is to test the hypotheses that: Subjects with GWI have reduced NAA in the basal ganglia and pons, which are not accounted for by confounds such as PTSD, depression, and alcohol abuse. Reduced NAA in basal ganglia and pons correlates with CNS signs and symptoms of GWl. Study procedures include a medical evaluation, clinical assessments, neurocognitive testing, startle testing, MRI/MRSI, and the "Haley Questionnaire." To date, we have studied a total of 253 subjects, 225 of whom have data for analysis. Of this total, 52 met criteria for GWl, 90 are controls, and 83 have an intermediate classification. Some preliminary data analysis has been performed.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2005
Accession Number
ADA443757

Entities

People

  • Michael W. Weiner

Organizations

  • Northern California Institute for Research and Education

Tags

DTIC Thesaurus Topics

  • Brain
  • Central Nervous System
  • Classification
  • Data Analysis
  • Department Of Defense
  • Depression
  • Education
  • Hypotheses
  • Magnetic Resonance
  • Mental Processes
  • Nervous System
  • Persian Gulf Syndrome
  • Questionnaires
  • Resonance
  • Signs And Symptoms
  • Spectroscopy

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Medical Imaging.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.