A Role for Vasopressin During Resuscitation of Traumatic Shock

Abstract

In the past few years, arginine vasopressin (AVP) has emerged as a rational alternative to catecholamines for the hemodynamic support of refractory vasodilatory shock and cardiopulmonary arrest. The therapeutic potential of AVP in traumatic shock is now being evaluated. Our laboratory investigations have revealed an apparent benefit of AVP when compared to standard fluid resuscitation in clinically relevant models of brain injury and chest injury. Further experimental work and subsequent clinical trials appear justified to validate the efficacy of AVP for resuscitation of trauma patients.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2004
Accession Number
ADA444899

Entities

People

  • Albert J. Varon
  • Ara J. Feinstein
  • David R King
  • Kenneth G. Proctor
  • Masamitsu Sanui
  • Stephen M. Cohn

Organizations

  • University of Miami

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Flow
  • Brain
  • Brain Injuries
  • Cardiac Arrest
  • Cardiopulmonary Resuscitation
  • Cardiovascular Physiological Phenomena
  • Combat Casualty Care
  • Health Services
  • Hemorrhage
  • Hemorrhagic Shock
  • Pituitary And Hypothalamic Hormones And Analogues
  • Resuscitation
  • Thoracic Injuries
  • Traumatic Shock
  • Wounds And Injuries

Fields of Study

  • Biology
  • Medicine
  • Psychology

Readers

  • Cardiovascular Physiology
  • Systems Analysis and Design