Integrated Cancer Research in Five Thematic Areas in Interest

Abstract

During the last FY of the award, the Cancer Institute of Long Island benefited from CPMRP funding in a manner consistent with the proposed activities of the award. In the area of core instrumentation acquisition, a Carl Zeiss Total Internal Reflection Fluorescence (TIRF) microscope has been ordered. This technology is vital to bridge the gap in CDMRP funded optics systems at Stony Brook, by providing cancer researchers with the capability to study localization at the cell membrane level. A new, state-of-the-art imaging system was requested via programmatic modification that was submitted and approved by CDMRP under separate cover; a Carl Zeiss Fluorescence Correlation Spectroscopy (FCS) Confocal Microscope, is operational and is being utilized to measure events at the single molecule level. The university has organized funds to construct a dedicated ISO Class 7 clean room to support the FCS Confocal Microscope. Consistent with the funding for this initiative were the granting of multi-year RSU packages, or Research Support Units. RSU's are a mechanism to ensure necessary support for junior faculty and work as enhancements to enable the successful establishment of their laboratories. Each RSU provided support for laboratory personnel, small or specialized research equipment, and supplies. During the last funding year three individuals were recruited into this initiative. The faculty designees for this activity are Howard Adler, MD, Assistant Professor of Urology (on-going RSU), Howard Crawford, PhD, Assistant Professor of Pharmacological Sciences (on-going RSU), Marjana Maletic-Savatic, MD-PhD, Assistant Professor of Neurology (new RSU). Dr. Adler is investigating the angiogenesis of prostate cancer from a translational approach. Dr. Crawford continues to make significant strides in understanding cell and protein signaling events in pancreatic and breast cancer. Dr. Maletic-Savtic is investigating the proliferation of brain carcinoma and demyelinating of neurons due

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2005
Accession Number
ADA446240

Entities

People

  • Craig C. Malbon

Organizations

  • State University of New York

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Cancer
  • Cell Physiological Processes
  • Cells
  • Confocal Microscopy
  • Diseases And Disorders
  • Health Services
  • Medical Personnel
  • Microscopes
  • Microscopy
  • Neoplasms
  • New York
  • Prostate Cancer
  • Stem Cells

Readers

  • Research Science/Academic Research