High Resolution X-Ray Phase Contrast Imaging with Acoustic Tissue-Selective Contrast Enhancement
Abstract
We show that ultrasound can be used for contrast enhancement in high-resolution x-ray imaging of tissue and soft materials. Interfacial features of objects are highlighted as a result of both the displacement introduced by the ultrasound and the inherent sensitivity of x-ray phase contrast imaging to density variations. We have performed preliminary theoretical calculations of the radiation force induced by a sound fields and compared it to our experimental results. Some further characteristics of the method are demonstrated by imaging Teflon beads embedded in agarose. Additionally, we have developed the theoretical and experimental tools required to perform tomography using acoustically modulated X-ray phase contrast imaging. Some preliminary 3D tests reported. We are now ready to perform the first 2D and 3D measurements of biological samples using acoustically modulated X-ray phase contrast imaging.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2005
- Accession Number
- ADA446330
Entities
People
- Gerald J. Diebold
Organizations
- Brown University