Targeting MRS-Defined Dominant Intraprostatic Lesions with Inverse-Planned High Dose Rate Brachytherapy

Abstract

During this first year, we have obtained CHR approval (December 2004) from the three step process (C.U., P.R.C. and C.H.R.) committees at UCSF. Patient enrollment will begin immediately after receiving CHR approval from D.O.D. The accuracy of aligning MRI/MSRI data acquired with different types of endorectal probes to images acquired without a probe was determined. A 94% Average overlap of prostate contours was obtained using rigid endorectal coil. We have also obtained a class solution for the boost of DIL defined by MRI/MRST and the maximum achievable boost level under clinical dosimetric requirements using data from 10 previously treated HDR brachytherapy patients.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2005
Accession Number
ADA447537

Entities

People

  • I-chow Hsu
  • Jean Pouliot
  • John Kurhanewicz
  • Sue Noworelski

Organizations

  • University of California, San Francisco

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Anatomy
  • Department Of Defense
  • Dose Rate
  • Electronic Mail
  • Genitalia
  • Image Registration
  • Magnetic Resonance
  • Medical Personnel
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Radiation Oncology
  • Radiotherapy
  • Three Dimensional
  • Two Dimensional
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Clinical Trial Research.
  • Medical Imaging.