Quarterly Performance/Technical Report of the National Marrow Donor Program
Abstract
Contract N00014-05-1-0859: 1. Contingency Preparedness: Collect information from transplant centers build awareness of the Transplant Center Contingency Planning Committee and educate the transplant community about the critical importance of establishing a nationwide contingency response plan. 2. Rapid Identification of Matched Donors : Increase operational efficiencies that accelerate the search process and increase patient access are key to preparedness in a contingency event. 3, Immunogenetic Studies: Increase understanding of the immunologic factors important in Hematopoietic Stem Cell (HSC) transplantation. 4. Clinical Research in Transplantation: Create a platform that facilitates multicenter collaboration and data management. Contract N00014-05-1-310: 1. Evaluate optimal short term storage parameters for stimulated and unstimulated leukapheresis (donor lymphocytes) and bone marrow products, including the type of storage media and the cell concentration, in addition to temperature and duration of storage before processing and infusion. 2. The National Marrow Donor Program (NMDP) has developed an algorithm that "predicts" high resolution HLA typing results on donor samples that exist in the Registry with only low or intermediate results reported. Perform validation of NMDP algorithm by selecting donors randomly that have low or intermediate DRB1 typing results and test the ability of the algorithm to predict KIR ligand mismatching in the absence of existing HLA-C locus results.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2006
- Accession Number
- ADA447552
Entities
People
- Judy W. Davis
- Patrica A. Coppo
- Steve M. Spellman
Organizations
- National Marrow Donor Program