Prostate Carcinoma Detection Using Combined Ultrasound Elasticity and Tissue Strain-Hardening Imaging

Abstract

The underlying hypothesis of our study is that remote, non-invasive measurements of prostate elasticity are possible and may increase the detection and/or characterization of potentially malignant masses in the prostate. The purpose of this study is to develop ultrasound technology to produce high-resolution strain images of the prostate for remote evaluation of the strain dependent elastic (Young's or shear) modulus. The main objective of our research program is to test the hypothesis that quantitative elasticity images of the prostate can be obtained using real-time ultrasound and manual deformation of the gland. To achieve this objective, we have developed speckle tracking algorithms and methods for strain and elasticity imaging of prostate. The developed imaging methods were tested using tissue-mimicking phantoms. Next, we will conduct experimental studies using tissue-containing phantoms, and well-defined clinical studies. At the conclusion of the study, a prototype of clinical imaging system will be designed.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2006
Accession Number
ADA448245

Entities

People

  • Stanislav Emelianov

Organizations

  • University of Texas at Austin

Tags

DTIC Thesaurus Topics

  • Acoustic Properties
  • Algorithms
  • Cancer
  • Cross Correlation
  • Detection
  • Diagnostic Imaging
  • Elastic Properties
  • Imaging Techniques
  • Measurement
  • Mechanical Properties
  • Medical Personnel
  • Modulus Of Elasticity
  • Prostate
  • Prostate Cancer
  • Strain Hardening
  • Three Dimensional
  • Ultrasounds

Fields of Study

  • Medicine
  • Physics

Readers

  • Mechanical Engineering/Mechanics of Materials.
  • Medical Imaging.