A Survey of Antiviral Drugs for Bioweapons: Review

Abstract

Smallpox (Variola major), and the haemorrhagic fever viruses (filoviruses and arenaviruses) are classified as Category A biowarfare agents by the Centers for Disease Control. Category A agents pose a significant risk to public health and national security because they can be easily disseminated by aerosol, although with the exception of variola, they are not easily transmitted from person to person. An attack with these viruses would result in high morbidity and mortality and cause widespread panic. With the exception of smallpox and Argentine haemorrhagic fever virus, there are no vaccines or approved treatments to protect against these diseases. In this review we focus on promising prophylactic, therapeutic and disease modulating drugs.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2005
Accession Number
ADA449343

Entities

People

  • Arthur J Goff
  • Jason Paragas

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Animal Diseases
  • Anti-Infective Agents
  • Antiviral Agents
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Chemotherapy
  • Disease Outbreaks
  • Dna Virus Infections
  • Health Services
  • Interferon
  • Lepidoptera
  • Microbiology
  • Pharmacology
  • Poxviridae Infections
  • Proteins
  • Viruses

Fields of Study

  • Medicine

Readers

  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology