Needle-Free Inhalable Vaccine and Antibiotic Powder Aerosols
Abstract
Multiple constituents can be incorporated in three fluids in a low volume cross to make heterogenous and homogenous nanoparticles and microparticles. " Pharmaceuticals, proteins, antibodies, and vaccines can be stabilized, dried, and micronized by a newly patented process, CAN-BD. " A SF nebulization, desolvation and coating method (CANBD) has been developed that can manufacture dry powders and coatings of many materials. " Coating and drying requires only seconds. " Water and many organic solvents yield nanoparticles and microparticles with unique compositions and properties. " Fluid ratios, pressures, and solute concentrations determine particle size.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 15, 2004
- Accession Number
- ADA449496
Entities
People
- J. L. Burger
- R. E. Sievers
- S. P. Cape
Organizations
- University of Colorado Boulder