Simultaneous Genomic Detection of Multiple Enteric Bacterial and Viral Pathogens, Including SARS-CoV and RVFV

Abstract

A multiplexed screening system to detect pathogenicity islands (PI) of bacteria causing enteric disease and pathogenicity factors (PF) associated with the SARS-associated coronavirus (SARS-CoV) and Rift Valley Fever Virus (RVFV) has been developed. Pathogenic bacteria contain DNA sequences (PI) that code for proteins enhancing the ability of the bacteria to cause disease in the host, while viruses possess genomic sequences (PF) that are associated with their pathogenicity. By quickly screening for multiple pathogenicity island and factor sequences, end-users will have the capability to detect the first signs of an enteric or viral bioattack without requiring screening for a particular organism.

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Document Details

Document Type
Technical Report
Publication Date
Nov 15, 2004
Accession Number
ADA449520

Entities

People

  • C. J. Peters
  • Christy Weiss
  • Kerry Oliver
  • Lenny Carruthers
  • Robert Chin
  • Shelley Payne
  • Shinji Makino
  • Steve Kornguth

Organizations

  • University of Texas at Austin

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acquisition
  • Anti-Bacterial Agents
  • Bacteria
  • Detection
  • Health Services
  • Infection
  • Infectious Diseases
  • Microbiomes
  • Molecules
  • Pathogenic Bacteria
  • Polymerase Chain Reaction
  • Proteins
  • Sars
  • Sequences
  • Virus Diseases
  • Viruses

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Oncology and Biomarker-Based Cancer Detection.
  • Virology (or Medical Virology).