Selective Binding of Organophosphate Pesticides Using Molecular Imprinted Polymers

Abstract

Molecular Imprinted Polymers (MIPs) have been used for recognition and binding of different compounds. We are developing MIPs to selectively bind organophosphate pesticides and toxic chemical warfare nerve agents. MIPs were made to the pesticide Dichlorvos. Control MIPs were made without the template. Dichlorvos-MIPs bound more Dichlorvos in comparison to control-MIPs. The Dichlorvos-MIPs can be regenerated after binding the pesticide and reused at least three times by repeating the washing procedure. Dichlorvos-MIPs demonstrated specificity for its template since these MIPs did not bind Methamidophos, Phosdrin, and Metasystox I, compounds with similar chemical structures to that of Dichlorvos.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2005
Accession Number
ADA449756

Entities

People

  • Ali M. Saboori
  • Richard K. Gordon

Organizations

  • Walter Reed Army Institute of Research

Tags

Communities of Interest

  • Weapons Technologies

DTIC Thesaurus Topics

  • Abstracts
  • Acetylcholinesterases
  • Alcohols
  • Alkenes
  • Biochemistry
  • Biological Sciences
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemical Weapons
  • Chemistry
  • Liquid Chromatography
  • Materials
  • Molecules
  • Nerve Agents
  • Organophosphates
  • Pesticides
  • Recognition

Readers

  • Neurotoxicology
  • Parallel and Distributed Computing.
  • Polymer Science and Technology