Cavitands: Molecules With Enhanced Selectivity for Chem/Bio Detection
Abstract
The selective response of supramolecular structures, cavitands, is demonstrated using a sensitive optical transduction scheme, surface plasmon resonance (SPR). The methylene bridged cavitands (MeCav) with shallow cavities do not complex aromatic vapors, the pyrazine bridged cavitands (PzCav) show intermediate selectivity whereas the quinoxaline bridged cavitands (QxCav) with the deepest cavities show the best selectivity for aromatic vapors. A comparison with polymer sensing layers, PECH and PIB, shows cavitands are more selective although the polymer layers were more than twice the thickness of spin coated cavitand layers. Cavitands are therefore promising materials for the selective detection of CW agents.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2005
- Accession Number
- ADA449775
Entities
People
- Devanand K. Shenoy
Organizations
- United States Naval Research Laboratory