Microarray-Based Resequencing of Multiple B. anthracis Isolates

Abstract

How can we detect and identify BW agents? (1) Genotype markers known to show variation: Fixed species specific variants, previously identified - Rapid detection of a small number of sites - Example: Real-time PCR (confirmatory Lab); (2) DNA sequence regions/genomes of interest: Maximally informative (The sequence is the genotype!) - Detects common and rare variants - Strain identification/origin (Definitive Lab); (3) The future detection and identification of BW agents will increasingly depend upon DNA sequencing technologies.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2005
Accession Number
ADA449782

Entities

People

  • Michael E. Zwick

Organizations

  • Naval Medical Research Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Detection
  • Dna Microarrays
  • Dna Sequence Analysis
  • Genetic Phenomena
  • Genetic Structures
  • Genetics
  • Genome
  • Genotypes
  • Identification
  • Information Operations
  • Medical Genetics
  • Sequences
  • Small Ships
  • Standards

Fields of Study

  • Biology

Readers

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