Multi-Array (trademark) Immunodetection of Biowarfare Agents Using the Meso Scale Discovery (trademark) Sector PR (trademark)

Abstract

Current bioanalysis roadmap supports an integrated approach for detection and identification using multiple technologies. The multi-array immunodetection system presented combines state-of-the-art immunoassay analysis (ORIGEN ECL) and nucleic acid analysis (SmartCycler Taqman). The briefing discusses four 15-min washed assays developed for use on the Sector PR, a bioassy platform from Meso Scale Discovery. Assay protocols have been developed for both washed and nonwashed formats. The nonwashed format is currently in development.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2005
Accession Number
ADA449896

Entities

People

  • Alan Zulich
  • Deborah Menking
  • Emily Myers
  • Fred Lee
  • Joseph Hamel
  • Kishna Mangaya
  • Michael Goode

Organizations

  • Edgewood Chemical Biological Center

Tags

Communities of Interest

  • Counter WMD

DTIC Thesaurus Topics

  • Antibodies
  • Assays
  • Biomedical And Dental Materials
  • Chemistry
  • Detection
  • Detectors
  • Dynamic Range
  • Electrodes
  • Equine Encephalitis
  • Homeland Defense
  • Immunoassay
  • Materials
  • Nucleic Acids
  • Polymer Chemistry
  • Polymeric Films
  • Ruthenium
  • Sensitivity

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Oncology and Biomarker-Based Cancer Detection.
  • Organizational Process Management (OPM).

Technology Areas

  • Biotechnology