Comparison of Blood Pressure and Thermal Responses in Rats Exposed to Millimeter Wave Energy or Environmental Heat
Abstract
Previous work suggests that sustained exposure to millimeter waves causes greater heating of skin and faster induction of circulatory failure than environmental heat (EH) exposure. We compared temperature changes in skin and the time to reach circulatory collapse in male Sprague-Dawley rats exposed to the following conditions in three separate experiments: (1) ER at 42 degrees C, 35 GHz at 75 mW/sq cm, or 94 GHz at 75 mW/ sq cm under ketamine and xylazine anesthesia; (2) ER at 43 degrees C, 35 GHz at 90 mW/sq cm, or 94 GHz at 90 mW/sq cm under ketamine and xylazine anesthesia; and (3) ER at 42 degrees C, 35 GHz at 90 mW/sq cm, or 94 GHz at 75 mW/sq cm under isoflurane anesthesia. In all experiments, temperature increase at the skin surface differed significantly in the rank order of 94 GHz> 35 GHz> EH. Time to reach circulatory collapse was significantly less only for rats exposed to 94 GHz at 90 mW/sq cm compared to both the 35 GHz at 90 mW/sq cm and the ER at 43 degrees C groups. The data indicate that body core heating is the major determinant of induction of hemodynamic collapse in this model of millimeter wave overexposure.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 22, 2005
- Accession Number
- ADA450288
Entities
People
- B. J. Brott
- C. Z. Cerna
- J. E. Kalns
- J. L. Kiel
- K. L. Ryan
- L. L. Soza
- Nancy J. Millenbaugh
- P. A. Mason
- R. V. Blystone
- W. S. Lawrence
Organizations
- General Dynamics Mission Systems