Unintended Smallpox Vaccination of HIV-1 Infected Individuals in the United States Military

Abstract

We identified 10 individuals who had undiagnosed human immunodeficiency virus type 1 (HIV-1) infection at the time of smallpox vaccination. Mean CD4 cell count was 483 cells/ mm3 (range, 286 751 cells/mm3), and mean log10 plasma HIV-1 RNA load was 4.13 copies/cm3 (range, 2.54 5.16 copies/ cm3). All vaccinees (3 primary and 7 repeat) had a normal, robust reaction without complications. Smallpox vaccine was well-tolerated in this small series of HIV-1 infected military personnel.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2004
Accession Number
ADA452944

Entities

People

  • Adam Armstrong
  • Brian K. Agan
  • Glenn A. Schnepf
  • Harold E. Caraviello
  • Judith Delmar
  • Mark R. Wallace
  • Mary Bavaro
  • Matthew Lim
  • Naomi Aronson
  • Sybil A. Tasker

Organizations

  • Naval Submarine Medical Research Laboratory

Tags

DTIC Thesaurus Topics

  • Blood
  • Diseases And Disorders
  • Health
  • Health Care
  • Health Services
  • Hiv Infections
  • Infectious Diseases
  • Lepidoptera
  • Lymphocytes
  • Medical Personnel
  • Military Personnel
  • Poxviridae Infections
  • Public Health
  • United States
  • Vaccination
  • Vaccines

Readers

  • Infectious Disease/Epidemiology
  • Mathematics or Statistics
  • Molecular Genetics

Technology Areas

  • Biotechnology