Detecting Bacteria by Direct Counting of Structural Protein Units by the Integrated Virus Detection System (IVDS) and Mass Spectrometry

Abstract

This report explores the direct counting of "hair-like" structures specific for gram-positive bacteria. Indications show that these structures are intact after their removal from the cell and are sufficiently different from species to species of bacteria to indicate bacteria type if not actual identification. Their detection would represent a new approach to bacteria detection and identification. This report documents the detection of the bacterial structures using the physical nanometer counting methodology in the Integrated Virus Detection System (IVDS) and Electrospray Ionization-Mass Spectrometry.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2006
Accession Number
ADA454255

Entities

People

  • Charles H. Wick
  • Patrick E. Mccubbin
  • Rabih E. Jabbour
  • Samir V. Deshpande

Organizations

  • Edgewood Chemical Biological Center

Tags

Communities of Interest

  • Counter WMD

DTIC Thesaurus Topics

  • Bacteria
  • Bacterial Proteins
  • Capillary Electrophoresis
  • Cells
  • Cellular Structures
  • Detection
  • Electrospray
  • Electrospray Ionization
  • Ionization
  • Liquid Chromatography
  • Mass Spectra
  • Mass Spectrometers
  • Mass Spectrometry
  • Microorganisms
  • Proteins
  • Spectrometry
  • Spectroscopy

Fields of Study

  • Biology

Readers

  • Computational Modeling and Simulation
  • Molecular and Cellular Biochemistry
  • Virology (or Medical Virology).