Unique Approaches to Androgen Effects on Prostate Cancer

Abstract

Sex hormone-binding globulin (SHBG) is a plasma protein that binds androgens. It also is a transducer of androgen signaling at the plasma membrane of prostate cancer cells. We have found that the human prostate cancer cell line, LNCaP, in addition to having a receptor for SHBG (RSHBG), produces its own SHBG. We hypothesize that local regulation

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2006
Accession Number
ADA454900

Entities

People

  • William Rosner

Organizations

  • Mount Sinai Morningside

Tags

DTIC Thesaurus Topics

  • Androgens
  • Blood Proteins
  • Cell Line
  • Cell Membrane
  • Cells
  • Cellular Structures
  • Gene Expression
  • Genetic Code
  • Health Services
  • Hormones
  • Medical Personnel
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Proteins
  • Sex Hormones
  • Tumor Cell Line

Fields of Study

  • Biology

Readers

  • Breast cancer cell signaling and growth regulation.
  • Prostate Cancer Biology.