Rapid Molecular Fingerprinting of Pathogens

Abstract

The first aim of this project was to identify a set of ligands that bind specifically to each member of a panel of related alpha viruses, namely, equine encephalitis viruses (EEV). The second aim was to develop a bacterial cell-based array platform that can be used to detect viruses present in serum or other complex mixtures. During the course of this project we generated a set of peptides that bind to Venezuelan or Western EEV (VEEV, WEEV), and investigated a microfluidic array method to pattern these affinity reagent displaying cells into arrays, allowing their potential application for detection assays.

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Document Details

Document Type
Technical Report
Publication Date
Aug 31, 2006
Accession Number
ADA455360

Entities

People

  • Patrick Daugherty

Organizations

  • University of California, Santa Barbara

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amino Acids
  • Bacterial Proteins
  • Blood Proteins
  • Cells
  • Chemical Engineering
  • Chemistry
  • Clones
  • Complex Mixtures
  • Cytokines
  • Detection
  • Electrodes
  • Encephalitis
  • Equine Encephalitis
  • Escherichia Coli
  • Proteins
  • Viruses

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Virology (or Medical Virology).