Design of Nanostructured Biological Materials Through Self-Assembly of Peptides and Proteins
Abstract
Introduction Self-assembly can be defined as the spontaneous organization of individual components into an ordered structure without human intervention [1""]. The key elements of molecular self-assembly are complementarity in shape among the individual components and weak, non-covalent interactions. Molecular self-assembly as a fabrication tool will have a significant impact in the coming decades. Engineering principles for micro- and nano-fabrication can be learned by understanding molecular self-assembly phenomena in nature. Numerous self-assembling systems have already been developed, ranging from block copolymers and surfactant-like materials to scaffolds for three-dimensional (3D) cell culture, DNA-based structures and models to study protein folding and protein conformational disease.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2002
- Accession Number
- ADA456045
Entities
People
- Davide M. Marini
- Shuguang Zhang
- Steve Santoso
- Wonmuk Hwang
Organizations
- Massachusetts Institute of Technology