Summer Student Breast Cancer Research Training Program

Abstract

The purpose of the Breast Cancer Research Training Program is to recruit and train potential future researchers in breast cancer research. During the 3-year grant, we recruited 75 applicants to the program, interviewed 22 candidates, and hired 15 students. Each year, students attended up to 7 research lectures, participated in weekly meetings, developed and carried out research projects under the supervision of their mentors, and presented their projects to a research audience. Projects conducted over the course of the grant built upon previous years' research. Ongoing research was conducted on the anticancer properties of an Asian mushroom, Ganoderma lucidum, upon highly invasive breast cancer cells, on the role of omega-3 fatty acids in preventing and treating breast cancer, and in the mechanisms by which C-reactive protein exerts its anticancer properties in breast cancer. Other projects addressed the effect of kinase inhibition on ERK activity in breast cancer cells, the role of the calpain proteolytic pathway in breast cancer-induced cachexia, and the inhibitory effects of a Japanese mushroom, Phellinus linteus, in breast cancer cells. These results have added significant new information to our understanding of dietary modulation of breast cancer and have provided 15 students with experience in breast cancer research.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2006
Accession Number
ADA456135

Entities

People

  • Gary P. Zaloga
  • Karen L. Spear

Organizations

  • Indiana University Health

Tags

DTIC Thesaurus Topics

  • Apoptosis
  • Biomedical Research
  • Breast Cancer
  • Cell Membrane
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Fatty Acids
  • Fish
  • Fish Oils
  • Immunoproteins
  • Inhibition
  • Lipids
  • Neoplasms
  • Oleic Acid
  • Plant Oils
  • Proteins

Fields of Study

  • Medicine

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Oncology (Cancer Research).
  • STEM Education