Multiple Aperture Radiation Therapy (MART) to Breast Cancer

Abstract

Compared with conventional methods for breast cancer RT such as opposed tangential fields (OTF), modern IMRT provides unprecedented potential to deliver 3D-dose distributions with superior tumor conformality and normal tissue spare. In practice, however, the current IMRT process deviates significantly from the conventional approach and requires considerable costs of the time and health care. The complexity of the treatment and deliver procedure make this technology problematic for the breast radiotherapy. We have carried out a systematic study on a new solution, which is a hybrid of the advantages of the IMRT and OTF, termed as multiple aperture radiotherapy (MART). The efficiency in dose shaping and simplicity in dose delivery make it a perfect choice for breast cancer treatment. A number of important milestones have been accomplished, which include (i) developed an efficient optimization method for MART inverse planning; (ii) implemented MART in a clinic environment for breast treatment; (iii) proposed a gated IMRT/MART based on the cutting-edge technology of 4D CT imaging; (iv) established a robust technique for low-dose 4D CT acquisition to reduce the risks of radiation-induced cancer. It is expected these tools will greatly facilitate the imaging, planning, delivery, and quality assurance of breast radiation treatment.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2005
Accession Number
ADA456141

Entities

People

  • Tianfang Li

Organizations

  • Stanford University

Tags

Communities of Interest

  • Air Platforms
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Computational Science
  • Detectors
  • Diagnostic Imaging
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Radiation Oncology
  • Radiotherapy
  • Tomography
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical or Health Care Field.
  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design