Fast Detection of Ciprofloxacin Resistance, Part I

Abstract

Fast DNA-based methods for detecting antibiotic resistance in bacteria were evaluated. The best method was adapted for use with several species, including Bacillus anthracis. The method was shown to be widely applicable, reliable, and performed within 90 minutes. DNA mutations associated with ciprofloxacin resistance were examined, and can be used to extend the method to other bacterial species.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2005
Accession Number
ADA457114

Entities

People

  • M. P. Broekhuijsen
  • W. C. Van Dijk

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Anti-Bacterial Agents
  • Bacteria
  • Bacterial Infections
  • Classification
  • Culture Media
  • Detection
  • Dna Sequence Analysis
  • Gram-Negative Bacteria
  • Infection
  • Medical Personnel
  • Melting Point
  • Mutations
  • Pathogenic Bacteria
  • Polymerase Chain Reaction
  • Sequence Analysis
  • Staphylococcus Aureus

Readers

  • Military/Explosive Ordnance Disposal (EOD) Technology
  • Molecular and genetic basis of cancer.
  • Systems Analysis and Design