Antimicrobial Cellulose: Preparation and Application of 5-Methyl-5-Aminomethylhydantoin

Abstract

A new N-halamine precursor, 5-methyl-5-aminomethylhydantoin (AH), was synthesized. This N-halamine precursor can be coated onto cotton surfaces with addition of the cross-linking agent butanetetracarboxylic acid (BTCA) and rendered biocidal by exposure to halogen solutions either before or after curing the coating or material. Standard washing tests show that covalently bound AH/BTCA on the cotton swatches can survive repeated washing cycles. After 50 washing cycles, chlorinated cotton swatches had lost 98.7% of oxidative C1+, but after rechlorination, almost 43.5% of C1+ was regained. Biocidal tests indicated that the cotton swatches coated with chlorinated AB/BTCA were effective against Gram positive Staphyloccus aureus and Gram negative Escherichil coli.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2006
Accession Number
ADA457450

Entities

People

  • Jifu Liang
  • Jung‐Hee Lee
  • L. Kou
  • R. M. Broughton
  • S. D. Worley
  • T. S. Huang

Organizations

  • Auburn University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force Research Laboratories
  • Anti-Infective Agents
  • Cellulose
  • Chemical Bonds
  • Chemical Synthesis
  • Chemistry
  • Chlorination
  • Chlorine
  • Contracts
  • Government Procurement
  • Governments
  • Information Exchange
  • Materials
  • Microorganisms
  • Polymers
  • Standards
  • Test Methods

Readers

  • Materials Science
  • Microbial Pathology
  • Surface Coatings Technology.