Concurrent MR-NIR Imaging for Breast Cancer Diagnosis

Abstract

The primary objective of this research program is to investigate concurrent near infrared (NIR) optical and magnetic resonance (MR) imaging for breast cancer diagnosis. The NIR diffuse optical imaging offers novel criteria for cancer differentiation with the ability to measure (in vivo) oxygenation and vascularization state, the uptake and release of contrast agents and chromophore concentrations with high sensitivity. However, NIR diffuse optical tomography is inherently a low spatial resolution imaging modality due to diffuse nature of light photons. Alternatively, MR provides high spatial resolution with excellent tissue discrimination, but has limited ability to monitor hemoglobin dynamics and other contrast mechanisms that optical imaging provides. Therefore, concurrent MRl-NlR optical imaging brings together the most advantageous aspects of the two imaging modalities for breast cancer diagnosis.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2006
Accession Number
ADA457699

Entities

People

  • Birsen Yazıcı

Organizations

  • Rensselaer Polytechnic Institute

Tags

Communities of Interest

  • Advanced Electronics
  • Energy and Power Technologies
  • Ground and Sea Platforms
  • Sensors

DTIC Thesaurus Topics

  • Breast Cancer
  • Cancer
  • Cardiovascular Physiological Phenomena
  • Computational Complexity
  • Computational Fluid Dynamics
  • Computational Science
  • Detection
  • Detectors
  • Differential Equations
  • Health Services
  • Kalman Filters
  • Magnetic Resonance
  • Mathematical Filters
  • Optical Properties
  • Oxygenation
  • Three Dimensional
  • Two Dimensional

Fields of Study

  • Physics

Readers

  • Medical Imaging.