Improved Sensitivity and Specificity for Detection of Prostate
Abstract
Amendment requests to the final approved HSRRB protocol were made to the local RB on July 21, 2005 which was finally approved in August of 2005 Meanwhile the registration algorithms were tested on resected prostates available from the pathology department Working with these prostates made it clear that the performance of the registration algorithms depended upon the accuracy with which the prostate was sliced in a parallel fashion and with uniform thickness This led to the development of the 'prostate slicer' which allowed us to cut the prostate into uniform 3mm parallel slices The recruitment of subjects began once the accuracy of the registration algorithms was tested to satisfaction We have to date recruited four subjects and competed scanning on three of them The fourth subject was claustrophobic and was unable to complete the imaging exam We have five subjects waiting in wings to be scanned in the month of June and July Meanwhile the RB protocol has been submitted for renewal as it expires on June 19, 2006 No changes were made to the protocol for its renewal In essence we have completed all requirements for Specific Aim 1 of the project We anticipate recruiting about 5 subjects a month, which will allow us to complete the data collection before December of 2006
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2006
- Accession Number
- ADA457792
Entities
People
- Elliott Siegel
- John Papadimitrou
- Michael Naslund
- Rao P. Gullapalli
Organizations
- University of Maryland, Baltimore