Polysaccharide Microarray Technology for the Detection of Burkholderia Pseudomallei and Burkholderia Mallei Antibodies

Abstract

A polysaccharide microarray platform was prepared by immobilizing Burkholderia pseudomallei and Burkholderia mallei polysaccharides. This polysaccharide array was tested with success for detecting B. pseudomallei and B. mallei serum (human and animal) antibodies. The advantages of this microarray technology over the current serodiagnosis of the above bacterial infections were discussed.

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Document Details

Document Type
Technical Report
Publication Date
Apr 27, 2006
Accession Number
ADA458492

Entities

People

  • David Deshazer
  • David M. Waag
  • Marilyn England
  • Narayanan Parthasarathy

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Bacteria
  • Bacterial Infections
  • Carbohydrates
  • Chemistry
  • Diseases And Disorders
  • Genomics
  • Gram-Negative Bacterial Infections
  • Infectious Diseases
  • Lipopolysaccharides
  • Liquid Chromatography
  • Microbiology
  • Polysaccharides
  • Proteins
  • Proteomics
  • Sars
  • Serodiagnosis

Fields of Study

  • Biology

Readers

  • Battery Technology and Engineering
  • Immunology
  • Molecular Genetics