Behavioral and Biological Effects of Housing Conditions and Stress in Male Rats - Relevance to Heart Disease
Abstract
The present experiment examined the effects of environmental enrichment and stress on behavioral and biological measures relevant to cardiovascular disease risk (i.e. plasma corticosterone levels elevated plus maze locomotor activity in an open field chamber body weight and food consumption and heart morphology). Seventy-two Sprague-Dawley rats were raised in enriched environments (social or social and physical enrichment) or non-enriched environments for a total of 48 days. Half of the animals were placed in stress conditions in which they received 14 days (20 minuteslday) of restraint stress and the other half of the animals were placed in a no-stress condition.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2006
- Accession Number
- ADA458977
Entities
People
- Sarah T. Shafer
Organizations
- Uniformed Services University of the Health Sciences