Effect of Acetazolamide on Leg Endurance Exercise at Sea Level and Simulated Altitude

Abstract

Acetazolamide can be taken at sea level to prevent acute mountain sickness during subsequent altitude exposure. Acetazolamide causes metabolic acidosis at sea level and altitude, and increase Sao2 (arterial oxygen saturation) at altitude. The aim of the present study was to determine whether acetazolamide impairs muscle endurance at sea level but not simulated altitude (4300 m for <3 h).

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2006
Accession Number
ADA459470

Entities

People

  • Allen Cymerman
  • Charles S. Fulco
  • Dan Ditzler
  • Eric Lammi
  • Steven F. Lewis
  • Steven R. Muza

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

DTIC Thesaurus Topics

  • Acetazolamide
  • Acid-Base Imbalance
  • Altitude
  • Anticonvulsants
  • Mountains
  • Oxygenation
  • Saturation
  • Sea Level

Readers

  • Cardiovascular Physiology
  • Marine Mammal Biology