A Training Program in Breast Cancer Research Using NMR Techniques

Abstract

This is a six year training program in breast cancer research using NMR techniques. This program has supported seven predoctoral students and five postdoctoral students. All the trainees have learned the theory and instrumentation of MRI. They have been actively involved in one of the seven research projects: (1) NMR studies of phosphorus metabolites of breast cancer cells using an improved cell perfusion system (2) Segmentation of mammographic masses (3) Establishment of an image database for computer-aided-diagnosis (CAD) research development (4) F19 NMR detection of trifluoperazine crossing Blood-Brain-Barrier through Pgp modulation (5) Tumor-targeted MR Contrast Enhancement by Anti-transferrin Receptor scFv-Immunoliposome Nanoparticles (6) MRI and histological correlations of cortical brain volumes in APP/PS1 mice (7) Enhanced molecular imaging with fused optical and MRI images. The trainees have attended the weekly seminars in the Cancer Center and also attended a special NMR seminar series in the Department of Radiology. Eight papers have been published and 16 abstracts have been presented in the national and international meetings. Five grants including a USAMRMC postdoctoral award have received.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2006
Accession Number
ADA459727

Entities

People

  • Paul C Wang

Organizations

  • Howard University

Tags

DTIC Thesaurus Topics

  • Blood
  • Breast Cancer
  • Cancer
  • Chemical Synthesis
  • Chemistry
  • Computer-Aided Diagnosis
  • Detectors
  • Health Services
  • Information Systems
  • Medical Personnel
  • Neural Networks

Fields of Study

  • Medicine

Readers

  • Medical Imaging.
  • Oncology (Cancer Research).
  • STEM Education

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech