Enhancing Bone Accretion Using Short Duration, Low-Level Mechanical Vibrations
Abstract
The etiology of the stress fracture syndrome is incompetely understood but it is clear that skeletons with high peak bone quantity and quality will be better pretected against incurring this crippling condition. In our one-year report, the ability of low-level whole body vibrations to decrease the levels of osteoclastic resorption and to enhance osteoblastic activity in the adolescent mouse skeleton, in the absence of detrimental side-effects on growth or the chemical composition of the matrix, was described. In this second annual report, data are presented that indicate that the efficacy of extremely low-level whole-body mechanical vibrations can be enhanced by altering the number of daily loading sessions or the magnitude of the acceleration. In summary, an extremely low-level mechanical stimulus, inducing deformations orders of magnitude below those that can actually damage bone, is capable of decreasing bone resorption and enhancing bone morphology effects that may help to reduce the incidence of stress fractures and to avoid skeletal pathologies later in life.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2005
- Accession Number
- ADA459736
Entities
People
- Stefan Judex
Organizations
- State University of New York