Software Tool for Analysis of Variance of DNA Microarray Data

Abstract

This report describes a software tool for two-way analysis of variance(ANOVA) with repeated measures on one factor for use in a multitude of problems, including the analysis of Affymetrix GeneChip TM microarry data. The proposed software has been used to analyze more than 22,000 probe sequences in less than 1 minute. The tool is entirely written in Java and as a result, is platform-independent. The current implementation of the tool only allows for one-way and two-way ANOVA. However, the internal data structure is designed to be able to hold data for multi-way ANOVA. The output is written to a tab-delimited test file and, accordingly, the tool can be easily extended to save the results directly into a relational database.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2006
Accession Number
ADA460048

Entities

People

  • Craig M. Lilly
  • Dechang Chen
  • Jaques Reifman
  • Larry A. Sonna
  • Purvesh Khatri

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

DTIC Thesaurus Topics

  • Analysis Of Variance
  • Data Science
  • Databases
  • Digital Data
  • Digital Information
  • Dna Microarrays
  • Information Science
  • Mathematics
  • Platforms
  • Relational Databases
  • Sequences

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Database Systems and Applications
  • Oncology and Biomarker-Based Cancer Detection.